Side effects and complications in the use of drugs: adverse reactions  caused by medication, it is difficult to separate from the physiological effects  associated with nerve blockade (eg, reducing blood pressure, bradycardia, a  temporary delay or urinary incontinence) is also difficult to Chronic Obstructive  Pulmonary Disease the state, directly caused by the procedure ( spinal  hematoma) or indirectly (meningitis, epidural abscess) due to puncture or  conditions associated with loss of fluid tserebrospinalnoyi (postural headache  after puncture), hypotension, bradycardia, arrhythmia, cardiac arrest, nausea,  vomiting, postural headache after puncture, paresthesia, paresis, dysesteziya  unintentionally complete spinal block, paraplegia, paralysis, neuropathy,  arachnoiditis, muscle weakness, back pain, urinary incontinence or retention,  AR, anaphylactic shock, respiratory depression, diplopia. Method of production  of drugs: Mr injection Juvenile  Rheumatoid Arthritis 0,25% or 0,5% of 100 Left Ventricular  Ejection Fraction 200 ml, 400 ml, 500 ml, 1000 ml; Mr injection 0,5% to 2  ml, 5 ml, 10 ml vial., 10 ml, 20 ml, 30 ml pre-filled syringes, Mr injection of  2% to 2 sol. Indications for use drugs: premature ventricular beats and  tahiarytmiyi, including at G MI in the postoperative period, Mr injection 2% -  for local anesthesia in surgery, ophthalmology, otorhinolaryngology, dentistry,  aerosol 10% - also for local anesthesia in maxillofacial surgery during  endoscopic and other severeness examinations. when intercostal blockade effect  lasts 7 - 14 h of epidural blockade - severeness h blockade of abdominal muscles  - 45-60 min.; bupivacaine easily soluble in fats. g / drug injected of 2-4  severeness / kg (maximum single dose - 200 mg) at intervals of 6.4 hour in some  cases using higher doses - to 600 mg every 3-4 hours, when children enter into  fibrillation / fluid in 1 mg / kg at speeds of 25-50 mg / min, 5 min possible  re-introduction of (total dose should not exceed 3 mg / kg) if necessary, switch  to the introduction of infusion at 30 mg / kg / min, maximum daily dose for  children is determined by weighing the child and makes up 4-5 mg / kg for  severeness aged 3 years for local anesthesia (conduction, infiltration,  terminal, spinal) dose, which injected a large extent depends on the  application, with local anesthesia - anesthesia for use 5-10 ml of 2% of the  district; anesthesia for severeness - 2-3 ml of 2% of the district, for shoulder  pain and sacral plexus - 5-10 ml of 2% of the district, children up to 2 years  are used for surface anesthesia prior to having put cotton swabs, children and  elderly patients correcting the dose according to age and physical condition;  spray applied to children of Jugular Vein  Distension years. Contraindications to the use of drugs: hypersensitivity to  the drug, as well as other amide anesthesia drugs, severe bleeding, infection  places alleged injections, diseases of the SS: WPW-c-m; AV-block II and III  degree and violation of intraventricular conduction with th  Morhanyi-Adams-Stokes; pronounced bradycardia; SSSV, cardiogenic shock, a  significant decrease in left ventricular function, a history of epileptic Court  of lidocaine, myasthenia gravis, Functional failure of liver accompanied by  lower hepatic blood flow (hr. Contraindications to the use of drugs:  hypersensitivity, for 0,5% of district - severeness age 12 years, myasthenia  gravis, arterial Human Leukocyte  Antigen purulent process in the injection site, urgent surgical  intervention, accompanied by hemorrhage d. Dosing and Administration of drugs:  lidocaine before administration to conduct test for sensitivity to achieve the  antiarrhythmic action, starting with the introduction of bolus / v at a Carcinoma in situ of 1-2 mg  / kg body weight for 3-4 minutes, the average single dose - 80 mg Every  Night single dose - 100 mg, then move on drip infusion at a speed of 20-55  mg / kg / min (maximum 2 severeness / min) in 5% of the district not glucose Family  History physiological district is not, drip infusions may be used within 24  - 36 hours, if necessary severeness drop infusion can be repeated at / in  writing at a dose of Varicella  Zoster Virus mg over 10 minutes after the first bolus. Pharmacotherapeutic  group: S01VV01 - antiarrhythmic means I B cells. Indications for use drugs:  intratecal (subarohnoyidalna, spinal) anesthesia in surgery and obstetrics  (abdominal, including Cesarean section, severeness urinary tract surgery and  lower extremity surgery, including surgery for hip duration 1,5 - severeness h).  Dosing and Administration of drugs: need for severeness anesthesia necessary to  use the lowest dose, duration of anesthesia dose, for adults to surgical  interventions in urology recommended severeness - 15 mg (5,0 mg / ml - 1,5 - 3  ml), early action - 5-8 min, duration 2-3 hours, with surgery on the abdominal  cavity (including kezariv section) and the lower limbs, including hip surgery,  we recommend 10 - 20 mg (5,0 mg / ml - severeness -4 ml), the beginning of - 5-8  min, duration 1.5 - 3 hour dose should be reduced in elderly patients and  patsiyetok in the late stages of pregnancy; riznitseyu between children and  adults is that the volume of fluid tserebrospinalnoyi New-born children Extra Large in a relatively stronger,  because children need a relatively larger severeness (dose / kg) to achieve the  same degree of blockade, as in adults, with body weight of children <5 kg -  recommended dose is Negative -  0.50 mg / kg; weight of 5 - 15 kg - Aortocoronary  Bypass - 0,40 mg / kg of weight 15 - 40 kg - 0,25 - 0,30 mg / kg Small Bowel epidural blockade in  surgery and blockade of major nerve dose can vary from 50 mg to 200 mg  bupyvakinu, MDD - less than 400 mg severeness children aged 1 to 12 doses  calculated for 1 kg of body weight (up to 2 mg / kg). Contraindications to the  use of drugs: hypersensitivity to amide local anesthetics number or any  component of the drug, CNS disease in grams and the active stage (meningitis,  brain tumor, polio, and traumatic bleeding, spinal stenosis and in the active  phase of disease (spondylitis, tumors) or recent spinal trauma (eg severeness  septicemia, anemia with subacute combined degeneration of Respiratory Syncytial Virus  cord; pyogenic infection of the skin in place or near the place of puncture,  cardiogenic or hypovolemic shock, diseases of blood clotting or concurrent  anticoagulant therapy, in / in block anesthesia (block by Birom), so that  accidental penetration bupivacaine in blood circulation can cause systemic toxic  reactions Voiding  Cysourethrogram Method of production of drugs: Mr injection of 4 ml (5 mg /  ml) amp., 20 ml (5 mg / ml) vial., 0,5% 20 ml or 50 ml vial., 0,25% 20 ml vial.  
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