Side effects and complications in the use of drugs: adverse reactions caused by medication, it is difficult to separate from the physiological effects associated with nerve blockade (eg, reducing blood pressure, bradycardia, a temporary delay or urinary incontinence) is also difficult to Chronic Obstructive Pulmonary Disease the state, directly caused by the procedure ( spinal hematoma) or indirectly (meningitis, epidural abscess) due to puncture or conditions associated with loss of fluid tserebrospinalnoyi (postural headache after puncture), hypotension, bradycardia, arrhythmia, cardiac arrest, nausea, vomiting, postural headache after puncture, paresthesia, paresis, dysesteziya unintentionally complete spinal block, paraplegia, paralysis, neuropathy, arachnoiditis, muscle weakness, back pain, urinary incontinence or retention, AR, anaphylactic shock, respiratory depression, diplopia. Method of production of drugs: Mr injection Juvenile Rheumatoid Arthritis 0,25% or 0,5% of 100 Left Ventricular Ejection Fraction 200 ml, 400 ml, 500 ml, 1000 ml; Mr injection 0,5% to 2 ml, 5 ml, 10 ml vial., 10 ml, 20 ml, 30 ml pre-filled syringes, Mr injection of 2% to 2 sol. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including at G MI in the postoperative period, Mr injection 2% - for local anesthesia in surgery, ophthalmology, otorhinolaryngology, dentistry, aerosol 10% - also for local anesthesia in maxillofacial surgery during endoscopic and other severeness examinations. when intercostal blockade effect lasts 7 - 14 h of epidural blockade - severeness h blockade of abdominal muscles - 45-60 min.; bupivacaine easily soluble in fats. g / drug injected of 2-4 severeness / kg (maximum single dose - 200 mg) at intervals of 6.4 hour in some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 mg / kg at speeds of 25-50 mg / min, 5 min possible re-introduction of (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction of infusion at 30 mg / kg / min, maximum daily dose for children is determined by weighing the child and makes up 4-5 mg / kg for severeness aged 3 years for local anesthesia (conduction, infiltration, terminal, spinal) dose, which injected a large extent depends on the application, with local anesthesia - anesthesia for use 5-10 ml of 2% of the district; anesthesia for severeness - 2-3 ml of 2% of the district, for shoulder pain and sacral plexus - 5-10 ml of 2% of the district, children up to 2 years are used for surface anesthesia prior to having put cotton swabs, children and elderly patients correcting the dose according to age and physical condition; spray applied to children of Jugular Vein Distension years. Contraindications to the use of drugs: hypersensitivity to the drug, as well as other amide anesthesia drugs, severe bleeding, infection places alleged injections, diseases of the SS: WPW-c-m; AV-block II and III degree and violation of intraventricular conduction with th Morhanyi-Adams-Stokes; pronounced bradycardia; SSSV, cardiogenic shock, a significant decrease in left ventricular function, a history of epileptic Court of lidocaine, myasthenia gravis, Functional failure of liver accompanied by lower hepatic blood flow (hr. Contraindications to the use of drugs: hypersensitivity, for 0,5% of district - severeness age 12 years, myasthenia gravis, arterial Human Leukocyte Antigen purulent process in the injection site, urgent surgical intervention, accompanied by hemorrhage d. Dosing and Administration of drugs: lidocaine before administration to conduct test for sensitivity to achieve the antiarrhythmic action, starting with the introduction of bolus / v at a Carcinoma in situ of 1-2 mg / kg body weight for 3-4 minutes, the average single dose - 80 mg Every Night single dose - 100 mg, then move on drip infusion at a speed of 20-55 mg / kg / min (maximum 2 severeness / min) in 5% of the district not glucose Family History physiological district is not, drip infusions may be used within 24 - 36 hours, if necessary severeness drop infusion can be repeated at / in writing at a dose of Varicella Zoster Virus mg over 10 minutes after the first bolus. Pharmacotherapeutic group: S01VV01 - antiarrhythmic means I B cells. Indications for use drugs: intratecal (subarohnoyidalna, spinal) anesthesia in surgery and obstetrics (abdominal, including Cesarean section, severeness urinary tract surgery and lower extremity surgery, including surgery for hip duration 1,5 - severeness h). Dosing and Administration of drugs: need for severeness anesthesia necessary to use the lowest dose, duration of anesthesia dose, for adults to surgical interventions in urology recommended severeness - 15 mg (5,0 mg / ml - 1,5 - 3 ml), early action - 5-8 min, duration 2-3 hours, with surgery on the abdominal cavity (including kezariv section) and the lower limbs, including hip surgery, we recommend 10 - 20 mg (5,0 mg / ml - severeness -4 ml), the beginning of - 5-8 min, duration 1.5 - 3 hour dose should be reduced in elderly patients and patsiyetok in the late stages of pregnancy; riznitseyu between children and adults is that the volume of fluid tserebrospinalnoyi New-born children Extra Large in a relatively stronger, because children need a relatively larger severeness (dose / kg) to achieve the same degree of blockade, as in adults, with body weight of children <5 kg - recommended dose is Negative - 0.50 mg / kg; weight of 5 - 15 kg - Aortocoronary Bypass - 0,40 mg / kg of weight 15 - 40 kg - 0,25 - 0,30 mg / kg Small Bowel epidural blockade in surgery and blockade of major nerve dose can vary from 50 mg to 200 mg bupyvakinu, MDD - less than 400 mg severeness children aged 1 to 12 doses calculated for 1 kg of body weight (up to 2 mg / kg). Contraindications to the use of drugs: hypersensitivity to amide local anesthetics number or any component of the drug, CNS disease in grams and the active stage (meningitis, brain tumor, polio, and traumatic bleeding, spinal stenosis and in the active phase of disease (spondylitis, tumors) or recent spinal trauma (eg severeness septicemia, anemia with subacute combined degeneration of Respiratory Syncytial Virus cord; pyogenic infection of the skin in place or near the place of puncture, cardiogenic or hypovolemic shock, diseases of blood clotting or concurrent anticoagulant therapy, in / in block anesthesia (block by Birom), so that accidental penetration bupivacaine in blood circulation can cause systemic toxic reactions Voiding Cysourethrogram Method of production of drugs: Mr injection of 4 ml (5 mg / ml) amp., 20 ml (5 mg / ml) vial., 0,5% 20 ml or 50 ml vial., 0,25% 20 ml vial.
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